Population
Turkey gizzard myosin (20,000-dalton light chain of smooth muscle myosin)
Design
Preclinical
Key result
At high concentrations of myosin light chain kinase, a second site on the 20,000-dalton light chain of smooth muscle myosin is phosphorylated, identified as threonine 18.
Authors
Loading...
Supports expanded MLCK substrate mapping in vitro; leaves open physiological or therapeutic relevance in vascular smooth muscle.
Identifies threonine 18 as the second phosphorylation site on the 20,000-dalton light chain of smooth muscle myosin by myosin light chain kinase and details its kinetics.
Ikebe et al. (1986) studied this question. Myosin light chain kinase was evaluated on Phosphorylation of a second site on the 20,000-dalton light chain of smooth muscle myosin. At high concentrations of myosin light chain kinase, a second site on the 20,000-dalton light chain of smooth muscle myosin is phosphorylated, identified as threonine 18.