Key points are not available for this paper at this time.
C−H bond activation of imines by an iridium complex is the decisive step in the three-component coupling reaction of an aldehyde, an amine, and an alkyne Eq. (1). The aldehyde and amine initially react to provide an imine, which in turn reacts with the alkyne to form the coupling product.
Sakaguchi et al. (Mon,) studied this question.