Key result
A 63-year-old woman with pulmonary artery intimal sarcoma exhibiting rare skip-like nodules and creeping intimal infiltration underwent left pneumonectomy and vascular reconstruction, surviving for 5 years and 3 months.
Why the study?
Complete surgical resection is crucial for favorable outcomes in rare pulmonary artery intimal sarcoma, but intraoperative delineation of tumor extent remains challenging.
Case Report (n=1)
No
Pulmonary artery intimal sarcoma can exhibit skip-like nodules and subtle creeping infiltration, necessitating comprehensive intraoperative and pathological assessments to achieve complete resection.
INTRODUCTION: Pulmonary artery intimal sarcoma (PAIS) is a rare vascular malignancy. Complete surgical resection is crucial for favorable outcomes; however, intraoperative delineation of the tumor extent poses a significant challenge. CASE PRESENTATION: A 63-year-old woman with suspected PAIS underwent a left pneumonectomy under cardiopulmonary bypass. Despite macroscopically clear margins, histopathological examination of the pulmonary artery (PA) stump exhibited tumor infiltration, necessitating reevaluation. We identified multiple skip-like intraluminal nodules along the PA and performed resection and subsequent reconstruction utilizing an autologous pericardial patch. The final pathology demonstrated not only nodular lesions but also creeping intimal infiltration in segments without gross abnormalities. CONCLUSIONS: Although PAIS typically exhibits contiguous spread along the intima, the presence of skip-like nodules and subtle creeping infiltration is rare, complicating intraoperative assessment. Comprehensive intraoperative and pathological assessments are essential to achieve a complete resection.
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Akazawa et al. (2025) conducted a case report in Pulmonary artery intimal sarcoma (n=1). Left pneumonectomy and vascular reconstruction was evaluated on Clinical outcome. A 63-year-old woman with pulmonary artery intimal sarcoma exhibiting rare skip-like nodules and creeping intimal infiltration underwent left pneumonectomy and vascular reconstruction, surviving for 5 years and 3 months.
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