Key result
This review summarizes the histopathology, evaluation, treatment, and prognosis of primary pulmonary hypertension, noting its insidious onset and generally disappointing pharmacologic treatment options.
This review summarizes the histopathology, evaluation, treatment, and prognosis of primary pulmonary hypertension in adults.
Offers clinicians a synthesized reference on primary pulmonary hypertension; leaves open the need for updated prospective trials on therapies.
Primary pulmonary hypertension is an enigmatic disease found predominantly in young women, but it also affects a significant number of middle-aged and elderly males and females. Its onset, characterized by progressively worsening dyspnea, fatigue, and chest pain, is insidious. Three distinct histopathologic subtypes have been identified, and the natural history of the disease process has been well-defined. Pharmacologic treatment options have, in general, been disappointing, and it appears that heart-lung transplantation will be applied only to a small minority of young patients with primary pulmonary hypertension in the near future. We review the histopathology, evaluation, treatment, and prognosis of primary pulmonary hypertension.
No takes yet. Share an insight, caveat, or question.
Hawkins et al. (1990) conducted a review in Primary pulmonary hypertension. This review summarizes the histopathology, evaluation, treatment, and prognosis of primary pulmonary hypertension, noting its insidious onset and generally disappointing pharmacologic treatment options.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
More from Clinical Cardiology