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July 20, 2023EP Europace43 citationsOpen Access

Deep sedation protocol during atrial fibrillation ablation using a novel variable-loop biphasic pulsed field ablation catheter

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Why the study?

Does a deep sedation protocol provide safe and effective sedation in patients undergoing pulsed field ablation for atrial fibrillation?

Population

29 patients with paroxysmal atrial fibrillation undergoing pulsed field ablation enrolled as part of the…

Design

Cohort

Follow-up

Intraoperative

Key result

A deep sedation protocol during pulsed field ablation for atrial fibrillation was safe and effective, achieving a RASS score of -1 to -5 in 93% of patients with no procedural complications.

Authors

MGMassimo GrimaldiElectrophysiologyFQFederico QuadriniOspedale Generale Regionale Francesco MiulliNCNicola CaporussoOspedale Generale Regionale Francesco Miulli

Discussion

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Overview

PFA may offer a nonthermal option for paroxysmal AF; leaves open durability, comparative efficacy, and broader safety in randomized trials.

Study Design

Type

Observational (n=29)

Structured PICO

Does a deep sedation protocol provide safe and effective sedation in patients undergoing pulsed field ablation for atrial fibrillation?

P
Population
29 patients (mean age 55 years, 28% female) with paroxysmal atrial fibrillation undergoing pulsed field ablation using a deep sedation protocol.
E
Exposure
Deep sedation protocol during pulsed field ablation using a variable-loop circular catheter.
O
Outcome
Safety and effectiveness of the sedation protocol assessed by Richmond Agitation-Sedation Scale (RASS), Visual Analogue Scale (VAS), Patient State Index (PSI), and Likert Scale Questionnaire (LSQ).patient reported

A deep sedation protocol is a safe and feasible alternative to general anesthesia during pulsed field ablation for atrial fibrillation.

Cite This Study

Grimaldi et al. (2023) conducted an observational in Paroxysmal atrial fibrillation (n=29). Deep sedation protocol was evaluated on Sedation efficacy (RASS score -1 to -5). A deep sedation protocol during pulsed field ablation for atrial fibrillation was safe and effective, achieving a RASS score of -1 to -5 in 93% of patients with no procedural complications.

synapsesocial.com/papers/6a6c30d43e46b6df0af34cb6https://doi.org/10.1093/europace/euad222
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