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July 31, 2026MMWR Surveillance SummariesOpen Access

Active Surveillance for Invasive Mold Disease — Four Hospitals, Atlanta, Georgia, 2020–2024

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Authors

ESElizabeth T. SajewskiCMCarolyn MackeySTStepy Thomas

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Overview

Randomized trial investigates invasive mold disease outcomes in immunocompromised individuals, suggesting urgent need for improved surveillance.

Key Points

  • This study aims to identify and classify cases of invasive mold disease (IMD) using active surveillance across four hospitals in Atlanta, Georgia.
  • Conducted active, laboratory-based surveillance for IMD from 2020 to 2024 at four hospitals in Atlanta, Georgia.
  • Identified potential IMD cases through laboratory records and classified them using MSG criteria.
  • Collected data on demographics, incidence rates, and treatment outcomes among patients diagnosed with IMD.
  • Out of 968 identified patients, 449 were classified as having IMD, including 20% MSG-proven and 32% MSG-probable cases.
  • Among IMD patients, 43% were admitted to ICU and the 90-day all-cause mortality rate was 45%.
  • 65% of patients had at least one host factor predisposing them to IMD, indicating that classic risk factors alone may miss many cases.

Cite This Study

Sajewski et al. (2026) studied this question.

synapsesocial.com/papers/6a6c46c0747664a1aa73ba2chttps://doi.org/10.15585/mmwr.ss7505a1
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