A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene ( LARS1 ) mutations with a histopathologic phenotype of neonatal hemochromatosis

We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic evidence of neonatal hemochromatosis in addition to a rare autosomal recessive disorder of infantile liver failure syndrome type 1.