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Examines connections between Ayurvedic Mamsa Dhatu and modern amino acid science, suggesting deeper insights into muscle metabolism.
This paper examines the convergence between Ayurveda's model of Mamsa Dhatu — muscle tissue nourished sequentially from digested food (Ahara Rasa) through tissue-specific metabolic fire (Dhatvagni) — and the modern biochemistry of protein: its molecular identity as chains of amino acids, the mTOR/leucine mechanism governing muscle protein synthesis, the 2025–2030 U.S. Dietary Guidelines revision that nearly doubled the recommended intake, the distinct disease mechanisms of kwashiorkor, marasmus, and sarcopenia (the last of which Ayurveda names Mamsa Dhatu Kshay), the ICMR-NIN data documenting a severe and largely unrecognised protein gap across Indian diets, and the comparative DIAAS/PDCAAS science separating protein sources the body genuinely absorbs from those that merely appear protein-rich on a label. It draws on recent peer-reviewed correlational work — Sharma, Sharma & Ankita (2026, JAIMS) and Bano, Sharma & Sharma (2024, IJHSR) — that has begun formally mapping Mamsa Dhatu onto contemporary muscle physiology. The governing argument: Mamsa Dhatu is not a poetic gloss for 'muscle.' It is a structurally accurate, centuries-early description of amino acid absorption and tissue-specific protein synthesis, arrived at through clinical observation rather than molecular instrumentation — and the two descriptions, read together, produce a more complete picture than either offers alone.
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Narayan Rout (2026) studied this question.
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