Mortality and major comorbidities in coeliac disease: implications for long-term care

Marco Vincenzo Lenti; Gino Roberto Corazza; Antonio Di Sabatino

doi:10.1016/j.lana.2026.101585

July 29, 2026The Lancet Regional Health - AmericasOpen Access

Mortality and major comorbidities in coeliac disease: implications for long-term care

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Key Points

The aim is to explore the mortality rates and major comorbidities associated with coeliac disease.
Reviewed the natural history of coeliac disease through existing literature.
Examined the relationship between coeliac disease and long-term health outcomes.
Coeliac disease is linked to an increased risk of mortality compared to the general population.
Major comorbidities associated with coeliac disease include conditions like osteoporosis and other autoimmune disorders.

Implication

Research reveals mortality and comorbidity risks in coeliac disease, indicating a need for improved long-term care strategies.

Abstract

Coeliac disease (CD) is a common enteropathy characterised by villous atrophy that is reversible in most cases following withdrawal of gluten from the diet.1 The clinical spectrum of CD ranges from asymptomatic cases to severe malabsorption syndrome. Despite its significant impact, the natural history of CD remains poorly understood, particularly its associated risk of mortality and comorbidities.

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Cite This Study

Lenti et al. (2026) studied this question.

synapsesocial.com/papers/6a6c5510747664a1aa73d6a2 https://doi.org/10.1016/j.lana.2026.101585

View Full Paper

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Mortality and major comorbidities in coeliac disease: implications for long-term care

Key Points

Implication

Abstract

Discussion

Cite This Study

Mortality and major comorbidities in coeliac disease: implications for long-term care

Key Points

Implication

Abstract

Discussion

Cite This Study

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