Key result
Elevated post-operative serum C-reactive protein levels (>175 mg/L) were associated with a higher rate of post-operative atrial fibrillation compared to levels ≤90 mg/L (35.1% vs 24.5%, P<0.0001).
Why the study?
Does elevated post-operative serum CRP predict the development of post-operative atrial fibrillation in patients undergoing CABG?
Does elevated post-operative serum CRP predict the development of post-operative atrial fibrillation in patients undergoing CABG?
Answers are grounded in this paper and cite their sources.
Elevated post-operative serum CRP levels are associated with a dose-dependent increased risk of developing post-operative atrial fibrillation following CABG.
We were interested to read Olesen et al.’s1 recent article, which describes the dose-dependent relationship between post-operative serum C-reactive protein (CRP) levels and development of post-operative atrial fibrillation (POAF) in patients who underwent coronary artery bypass graft surgery. Results showed a statistically significant difference (P < 0.0001) between the proportion of patients with POAF in the first serum CRP quartile (24.5% in CRP ≤90 mg/L) and fourth quartile (35.1% in CRP >175 mg/L). We commend the authors for their efforts and would like to draw a few useful comparisons between their study and similar studies that add additional weight to their findings. In Tanaka et al.’s2 prospective case–control study, an elevated serum CRP level in patients at baseline was found to correlate with an increased risk of developing AF. The crude incidence rate of AF per 1000 person-years increased from 0.6 for the lowest CRP...
No takes yet. Share an insight, caveat, or question.
Xie et al. (2020) conducted a letter in Post-operative atrial fibrillation. Elevated post-operative serum C-reactive protein (CRP) levels vs. Lower CRP levels (≤90 mg/L) was evaluated on Post-operative atrial fibrillation (POAF) (p=<0.0001). Elevated post-operative serum C-reactive protein levels (>175 mg/L) were associated with a higher rate of post-operative atrial fibrillation compared to levels ≤90 mg/L (35.1% vs 24.5%, P<0.0001).
Synapse has enriched 10 related papers. Consider them for comparative context: