Key result
Normalizing serum sodium resolves coved-type Brugada ECG pattern and symptoms within 10 hours.
Why the study?
Does correction of hyponatremia resolve the coved-type Brugada electrocardiogram pattern in patients with hyponatremia-induced Brugada syndrome?
Case Report (n=1)
No
Does correction of hyponatremia resolve the coved-type Brugada electrocardiogram pattern in patients with hyponatremia-induced Brugada syndrome?
Severe hyponatremia can transiently unmask the Brugada syndrome ECG pattern, mimicking an acute ST-segment elevation myocardial infarction that completely resolves upon sodium correction.
May warrant sodium correction in hyponatremia with Brugada pattern; leaves open generalizability beyond this case.
Seventy-three year-old male with history of diabetes, hypertension, and chronic kidney disease stage 3 presented with epigastric pain and hyponatremia. ECG showed new ST segment elevation at precordial leads consistent with Cove-type Brugada ECG pattern. Cardiac catheterization revealed non-significant coronary artery stenosis. He experienced pre-syncope and palpitations a year prior to admission with family history sudden cardiac death. Brugada syndrome was diagnosed. Cove-type Brugada ECG pattern and palpitations resolved with corrected sodium to 135.
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Rattanawong et al. (2021) conducted a case report in Brugada syndrome unmasked by hyponatremia (n=1). Correction of serum sodium was evaluated on Resolution of coved-type Brugada electrocardiogram pattern and symptoms. Correction of serum sodium from 126 mEq/L to 135 mEq/L completely resolved the coved-type Brugada ECG pattern and clinical symptoms within 10 hours.
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