Key result
Experimental subarachnoid hemorrhage impairs cerebrovascular response to hypercapnia at 1 week despite preserved baseline flow.
A technique is described for the production of subarachnoid haemorrhage in baboons and their subsequent recovery for chronic study of cerebrovascular reactivity. The baboons make complete neurological recoveries but the response of their cerebral circulation to hypercapnia is impaired one week later. Baseline values of cerebral blood flow and of cerebral oxygen consumption are unaffected at this time. There is no evidence of hypoxic brain damage.
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Boisvert et al. (1979) studied Subarachnoid haemorrhage. Production of subarachnoid haemorrhage was evaluated on Cerebrovascular response to hypercapnia. Experimental subarachnoid haemorrhage in baboons impaired the cerebrovascular response to hypercapnia 1 week later, though baseline cerebral blood flow and oxygen consumption remained unaffected.
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