Even notoriously unreactive substrates such as tetrasubstituted unfunctionalized olefins can be hydrogenated with high efficiency and excellent enantioselectivity using readily accessible chiral Ir catalysts. In this way, two adjacent stereogenic centers can be introduced in a single step (see scheme for an example; BArF=tetrakis(3,5-di(trifluoromethyl)phenyl)borate, o-Tol=ortho-tolyl).
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Schrems et al. (2007) studied this question.
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