Key result
Obstructive coronary artery disease was associated with a significantly higher prevalence of diastolic dysfunction compared to non-obstructive disease (83.3% vs 50.0%, p=0.001).
Why the study?
The study aimed to evaluate the relationship between the severity of CAD assessed by coronary multislice computed tomography and the degree of diastolic function.
Is obstructive coronary artery disease associated with worse left ventricular diastolic function compared to non-obstructive disease?
Cross-Sectional (n=80)
Yes
Is obstructive coronary artery disease associated with worse left ventricular diastolic function compared to non-obstructive disease?
Obstructive coronary artery disease is associated with a higher prevalence and severity of left ventricular diastolic dysfunction compared to non-obstructive disease.
Answers are grounded in this paper and cite their sources.
Supports diastolic function assessment in obstructive CAD; leaves open causality and prognostic impact in prospective studies.
Objectives: The aim of this study is to evaluate the relationship between severity of CAD by coronary mutlislice computed tomography scan and the degree of diastolic function Methods: The study consisted of 80 patients who underwent both coronary CTA and TTE within 1 year with no identifiable intervening cardiovascular event in National Heart Institute and Menoufia University Hospitals. All patients were subjected to detailed medical history, physical examination, full electrocardiography study including tissue Doppler imaging on mitral annulus, MSCT coronary angiography and different laboratory investigation as CBC, creatinine, lipid profile. Results: From 80 patients who have done both echocardiography examination and MSCT coronary angiography, the CT scan results were 38 patients with non-obstructive coronary artery disease and 42 patients with obstructive CAD, higher number of patients with diastolic dysfunction with higher values of E/E’, medial e’, lateral e’, LAVI (left atrial volume index) and TRV (tricuspid regurge velocity) were found in the group with obstructive coronary artery disease. Conclusion: Our study showed that diastolic dysfunction is more prevalent in patients with obstructive coronary artery disease with higher grade of diastolic dysfunction.
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ELShafey et al. (2020) conducted a cross-sectional in Coronary artery disease (n=80). Obstructive coronary artery disease vs. Non-obstructive coronary artery disease was evaluated on Prevalence of diastolic dysfunction (p=0.001). Obstructive coronary artery disease was associated with a significantly higher prevalence of diastolic dysfunction compared to non-obstructive disease (83.3% vs 50.0%, p=0.001).
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