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August 1, 2026Open Access

Recent Advances in Self-Nanoemulsifying Drug Delivery Systems (Snedds) for Improving the Oral Bioavailability of Poorly Water-Soluble Drugs: A Review

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Authors

SMSundaramoorthy K.2 Praveenkumar M.1*

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Overview

Review discusses formulation strategies and advancements in SNEDDS for enhancing drug absorption in challenging cases.

Key Points

  • The review aims to explore advancements in SNEDDS to enhance oral bioavailability of poorly water-soluble drugs.
  • Discussed fundamental principles of SNEDDS, including formulation component selection and mechanisms of self-emulsification.
  • Reviewed formulation development strategies and characterization techniques for SNEDDS.
  • Summarized recent advancements in liquid and solid SNEDDS and their pharmaceutical applications.
  • SNEDDS improve drug dissolution and absorption, potentially increasing oral bioavailability.
  • Recent advancements enhance the performance of poorly water-soluble drugs using lipid-based systems.
  • Highlighted challenges and proposed future directions for research in SNEDDS.

Cite This Study

Sundaramoorthy K.2 Praveenkumar M.1* (2026) studied this question.

synapsesocial.com/papers/6a6d9868e258b358b3c6bc42https://doi.org/10.5281/zenodo.21702787
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