Key result
Surgical excision of foot synovial sarcoma precedes tumor recurrence while awaiting neoadjuvant chemoradiation.
Why the study?
Synovial sarcoma presents challenges with accurate diagnosis or misdiagnosis.
Case Report (n=1)
This case report highlights the diagnostic challenges and rapid recurrence of monophasic synovial sarcoma in the foot.
Synovial sarcoma though a malignant soft tissue sarcoma of unknown histogenesis by definition, generally tends to arise about or near joints. By morphologic or histopathologic characterization, the subtypes identified are the biphasic, monophasic and undifferentiated or poorly differentiated variants. While the monophasic variant is the most common of the three, 10% of soft tissue sarcomas in all are represented by synovial sarcoma, and commonly affect the extremities. In view of the challenges of accurate diagnosis or misdiagnosis, we report a case of a left foot monophasic synovial sarcoma in a 28 year old male. The swelling which was initially painless, later showed pressure symptoms and was eventually subjected to surgical excision. The histopathological examination of the excised mass confirmed it to be a Monophasic synovial sarcoma. A recurrence developed while the patient was awaiting uptake of neo adjuvant chemo and radiation therapy.
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*1,2Akpor I. O., 3Joel J., 1Terkula D. G., 2Orhungur C., 4Ben-Ameh E. (2026) conducted a case report in Left foot monophasic synovial sarcoma (n=1). Surgical excision was evaluated on Recurrence. Surgical excision of a left foot monophasic synovial sarcoma in a 28-year-old male was followed by tumor recurrence while awaiting neoadjuvant chemotherapy and radiation therapy.
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