Consensus statement for the diagnosis and management of optic neuritis

This consensus statement provides a practical, step-by-step framework designed by 19 national specialists to standardize the care of optic neuritis. Recognizing that clinicians handle these cases differently depending on local resources, the guidelines offer a clear roadmap for distinguishing true optic nerve inflammation from its common clinical mimics. The primary focus is on identifying early “red flags,” optimizing neuroimaging protocols, and using targeted cell-based antibody testing to pinpoint the exact cause of the disease. Beyond immediate diagnosis, the paper outlines clear strategies for managing acute episodes with high-dose therapies, handling patients who do not respond to initial steroids, and establishing structured, long-term monitoring plans to track visual recovery. Because delayed or incorrect treatment can lead to permanent, irreversible nerve damage, this document serves as a reliable tool to help ophthalmologists make quick, safe, and effective clinical decisions for patient care.