E Macy, EW Ngor. J Allergy Clin Immunol: In Practice. 2013;1:258–263 To evaluate if it is adequate to identify clinically significant penicillin allergy by using only the commercially available penicilloyl-poly-lysine and penicillin skin tests followed by an oral amoxicillin challenge. A total of 500 sequential subjects with a history of penicillin allergy evaluated at the Kaiser Permanente Health Care Program were included in this study. A potential case of allergy to penicillin was defined as any penicillin class antibiotic allergy entry in the drug allergy section of the electronic medical record. The mean age of participants …
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Kattan et al. (2013) studied this question.