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March 1, 2000Arthritis & Rheumatism

A comparative study into the mechanisms of action of anti–tumor necrosis factor α, anti-CD4, and combined anti–tumor necrosis factor α/anti-CD4 treatment in early collagen-induced arthritis

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Authors

LML Marinova-MutafchievaImperial College LondonRWRichard WilliamsUniversity of OxfordCMClaudia MauriUniversity College London

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Marinova-Mutafchieva et al. (2000) studied this question.

synapsesocial.com/papers/6a6db2f231a3df8243271a32https://doi.org/10.1002/1529-0131(200003)43:3<638::aid-anr21>3.0.co;2-r
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: A comparative study using anti-TNFα, anti-IL-1α/β and IL-1Ra2008 · 506 citations
  2. 2Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors.1989 · 381 citations
  3. 3Treatment of Rheumatoid Arthritis with Single Dose or Weekly Pulses of Chimaeric Anti‐CD4 Monoclonal Antibody1992 · 72 citations
  4. 4A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture.1991 · 393 citations
  5. 5Decrease in cellularity and expression of adhesion molecules by anti–tumor necrosis factor α monoclonal antibody treatment in patients with rheumatoid arthritis1996 · 376 citations