ISAAC questionnaires were completed by the parents of 6432 children, aged 6-7 y and by themselves by 2864 children 13-14-y-old. Prevalence rates of respiratory and nasal symptoms and a diagnosis of asthma and hay fever were higher in 6-7-y-old boys than in girls, while girls aged 13-14 y had higher rates for most symptoms, except asthma. Underdiagnosis of asthma in 13-14-y-old girls cannot be excluded as an explanation, but our data suggest under-reporting of respiratory and nasal symptoms in 13-14-y-old boys.
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Wieringa et al. (1999) studied this question.
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