April 29, 2006Journal of the American Chemical Society193 citations

Kinetic Resolution of 2-Oxazolidinones via Catalytic, Enantioselective N-Acylation

VBVladimir B. Birman HJHui Jiang XLXimin Li

Key Points

Key points are not available for this paper at this time.

Abstract

Kinetic resolution of racemic 2-oxazolidinones via catalytic, enantioselective N-acylation has been achieved for the first time and with outstanding selectivities.

Perguntar à IA

Bookmark

View Full Paper

Cite This Study

Birman et al. (Sat,) studied this question.

synapsesocial.com/papers/6a6dceaffe4101aa97df9d5d https://doi.org/https://doi.org/10.1021/ja061560m

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Benzotetramisole: A Remarkably Enantioselective Acyl Transfer Catalyst2006 · 406 citations
2A New Synthetic Approach to (+)-Galantinic Acid, Degradation Product from the Peptide Antibiotic Galantin I, via 4-Amino-3-hydroxypyranose1990 · 24 citations
3Kinetic Resolution of Arylalkylcarbinols Catalyzed by a Planar-Chiral Derivative of DMAP: A New Benchmark for Nonenzymatic Acylation1998 · 211 citations
4The Kinetic Study on the Desulfurization of 4,5-trans- and 4,5-cis-5-Phenylthiooxazolidin-2-ones via Cyclic Carbamoloxyradical Species1990 · 5 citations
5Simple and Efficient N-Acylation Reactions of Chiral Oxazolidine Auxiliaries1996 · 55 citations

Perguntar à IA

Bookmark

View Full Paper