The oxidation of a primary alcohol to the corresponding carboxylic acid via permanganate and phase-transfer catalyst has been modified to circumvent impurity formation incurred during the reaction. A safe, simple, and efficient process was developed which gave the required carboxylic acid in 77% isolated yield using sodium permanganate in the presence of tetraethylammonium hydrogen sulphate.
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Mahmood et al. (1999) studied this question.
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