Key result
Finite element modeling of biopolymer stents showed dogboning of 31% to 46% compared to 62% for the Palmaz-Schatz metal stent, suggesting less potential arterial damage.
Why the study?
The study was conducted to address the mechanics of biopolymer coronary stents during deployment.
Computational modeling suggests that stent geometry has a greater impact on scaffolding than strut thickness or mechanical properties in biopolymer stents, which exhibit less dogboning than metal stents.
Model extends FEM tools to biopolymer stent mechanics; leaves open clinical translation and in vivo validation.
We used the finite element method-based toolbox COMSOL Multiphysics to address the important question of biopolymer coronary stent mechanics. We evaluated the diameter of the stent, the immediate elastic recoil, the dogboning and the foreshortening during deployment while using an idealized model that took into account the presence of the balloon and the coronary artery wall (equivalent pressure hypothesis). We validated our model using the well-known mechanics of the Palmaz–Schatz metal stent and acquired new data concerning a poly-L-lactic acid (PLLA) stent and some other biodegradable co-polymer-based stents. The elastic recoil was relatively high (26.1% to 31.1% depending on the biopolymer used) when taking into account the presence of both the balloon and artery. The dogboning varied from 31% to 46% for the polymer stents and was 62% for the metal stent, suggesting that less arterial damage could be expected with biopolymer stents. Various strut thicknesses were tested for the PLLA stent (114, 180 and 250[Formula: see text][Formula: see text]m) and no significant improvement in elastic recoil was observed. We concluded that the stent geometry has a greater impact on the scaffolding role of the structure than the strut thickness, or even the mechanical properties of the stent.
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Bokov et al. (2018) studied Coronary stent mechanics. Biopolymer coronary stents vs. Palmaz-Schatz metal stent was evaluated on Stent mechanics (elastic recoil, dogboning, foreshortening). Finite element modeling of biopolymer stents showed dogboning of 31% to 46% compared to 62% for the Palmaz-Schatz metal stent, suggesting less potential arterial damage.
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