A novel palladium-catalyzed intermolecular ditrifluoromethoxylation of unactivated alkenes has been developed, using a new electrophilic reagent, Selectfluor CN, as a strong oxidant, and AgOCF 3 as a trifluoromethoxide source. Preliminary mechanistic studies revealed that the reaction was possibly initiated by Pd(IV) species, and an unusual cis -addition of CF 3 O–Pd(IV) into the double bond leads to the formation of the first C–OCF 3 bond; in addition, the second C–OCF 3 bond was produced through reductive elimination at high-valent palladium center.
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Chen et al. (2018) studied this question.
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