The Role of Tumor Suppressor Genes in Molecular and Biological Basis of Lung Cancer

Lung cancer (LC) is the 2 nd most common cancer diagnosis by gender, behind prostate cancer for males and breast cancer for females [1]. The most common age of LC diagnosis is 70 years, whereas in most cases the prognosis is extremely poor as 17.4% of people in the United States that were diagnosed with LC survive five years after the diagnosis [2]. It is also responsible for a high rate of morbidity and mortality as advanced LC has extremely poor prognosis, with a 5-year survival of only 5% [1].