Key result
Magnetic resonance imaging parameters showed no significant correlation with foot dorsiflexor peak torque values (which ranged from 6 to 29 Nm) in patients with prior polio.
Why the study?
Do MRI findings of muscle degeneration correlate with isokinetic strength in foot dorsiflexors in patients with prior polio?
Observational (n=6)
Do MRI findings of muscle degeneration correlate with isokinetic strength in foot dorsiflexors in patients with prior polio?
In patients with prior polio, MRI signs of muscle degeneration do not significantly correlate with isokinetic strength, although severe MRI changes align with pronounced weakness.
Answers are grounded in this paper and cite their sources.
MRI may visualize patchy degeneration in post-polio weakness; leaves open its role for monitoring or prognosis in larger studies.
The thigh and lower leg of six patients with prior polio were examined using magnetic resonance imaging (MRI), and the strength of their weak foot dorsiflexors was measured isokinetically. Spinecho images of the lower extremities were visually evaluated on a semi-quantitative four-point scale, and T1 and T2 relaxation times of the lower leg anterior compartment were analysed. There were prominent MRI signs of randomly distributed muscle degeneration. The high signal intensity changes in the affected muscles on T1-weighted images and T1 and T2 values indicated replacement of muscle fibres with fat and the accumulation of tissue water, respectively. MRI findings were compared with isokinetic strength in foot dorsiflexor muscles. Foot dorsiflexor peak torque values at 30 deg/s ranged from 6 to 29 Nm. There was no significant correlation between MRI visual scoring, T1 and T2 relaxation times and peak torque values at 30 deg/s. However, the most severe MRI changes with visual scoring and T2 relaxation times were observed in the patients with the most pronounced muscle weakness.
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Tollbäck et al. (1996) conducted an observational in prior polio (n=6). Magnetic resonance imaging (MRI) of lower extremity muscles was evaluated on Correlation between MRI visual scoring, T1 and T2 relaxation times and peak torque values at 30 deg/s. Magnetic resonance imaging parameters showed no significant correlation with foot dorsiflexor peak torque values (which ranged from 6 to 29 Nm) in patients with prior polio.
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