to evaluate the influence of a sleep deprivation during the first part of the night on blood pressure (BP) and heart rate (HR) 12 healthy volunteers aged 24–30 yr (4 M and 8 F) underwent 2 ABPM (Spacelabs 90207, start at 2 p.m. and measurement every 15 min.) one week from each other. During the first one, subjects slept from 11 p.m. to 7 a.m., while during the second one they slept from 2:30 a.m. to 7 a.m. The main results are as follows: 1) During sleep BP and HR showed no differences between the two ABPM but at dawn, before awakening, SBP and DBP significantly lowered and HR significantly increased in restricted sleep regimen: this could be due to an increase of the amount of n-REM sleep to compensate the sleep deprivation: 2) After awakening and all the morning long, SBP and HR were significantly higher; it suggests that sleep deprivation could be a stressful event potentially dangerous for patients with coronary and cerebrovascular diseases.
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Paola Lusardi (1995) studied this question.