Key result
Culturing adult rat ventricular myocytes on laminin increased mitochondria per unit volume and reduced the transverse tubule system compared to culturing on plastic.
Culturing rat ventricular myocytes on laminin alters their ultrastructure, specifically increasing mitochondrial density in adult cells and reducing transverse tubules in both adult and neonatal cells compared to plastic.
No takes yet. Share an insight, caveat, or question.
May confound ultrastructure in rat myocyte models; leaves open optimal substrates for physiological relevance in cardiac research.
Delcarpio et al. (1989) studied this question. Culturing on laminin vs. Culturing on plastic was evaluated on Organelle volume densities (mitochondria and transverse tubules). Culturing adult rat ventricular myocytes on laminin increased mitochondria per unit volume and reduced the transverse tubule system compared to culturing on plastic.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: