Key result
Intravenous adenosine achieved reversion to sinus rhythm in 75% of all supraventricular tachycardia episodes and 96% of re-entrant episodes in children, with no serious side effects.
Why the study?
Does intravenous adenosine safely and effectively induce reversion to sinus rhythm in children with supraventricular tachycardia?
Observational (n=43)
Does intravenous adenosine safely and effectively induce reversion to sinus rhythm in children with supraventricular tachycardia?
Intravenous adenosine is safe and highly effective for terminating re-entrant supraventricular tachycardia in children, with a recommended starting dose of 0.1 mg/kg.
Answers are grounded in this paper and cite their sources.
Supports adenosine for pediatric SVT; leaves open need for randomized confirmation.
OBJECTIVE: To assess the efficacy and safety of adenosine in the management of supraventricular tachycardia in children. METHODOLOGY: A review of 43 children with supraventricular tachycardia who received intravenous adenosine between June 1992 and July 1995. RESULTS: Thirty-five patients had re-entrant supraventricular tachycardia and eight patients had atrial tachydysrhythmias. Reversion to sinus rhythm occurred in 75% of episodes in all patients treated for supraventricular tachycardia, and in 96% of episodes in patients with re-entrant supraventricular tachycardia. Early re-initiation of supraventricular tachycardia after reversion to sinus rhythm occurred in 25% of episodes. Sixteen percent of patients reverted with the recommended 0.05 mg/kg starting dose, and 35% reverted with a dose of 0.1 mg/kg. Four patients were given adenosine as a diagnostic procedure to elicit occult pre-excitation. The most common side effects were brief feelings of discomfort. No serious side effects occurred. CONCLUSION: Adenosine is safe and effective in the management of supraventricular tachycardia in children. A commencing dose of 0.1 mg/kg is appropriate.
No takes yet. Share an insight, caveat, or question.
SHERWOOD et al. (1998) conducted an observational in Supraventricular tachycardia (n=43). Intravenous adenosine was evaluated on Reversion to sinus rhythm. Intravenous adenosine achieved reversion to sinus rhythm in 75% of all supraventricular tachycardia episodes and 96% of re-entrant episodes in children, with no serious side effects.
Synapse has enriched 10 related papers. Consider them for comparative context: