Key result
Among adult Indonesian females, class II obesity was associated with significantly higher serum endothelin-1 levels compared to normoweight individuals (1.98 vs 1.53 pg/mL, p=0.030).
Why the study?
Obesity prevalence is increasing among adult Indonesian females and is linked to elevated endothelin-1 levels, prompting this study to investigate the association between serum endothelin-1 levels and obesity in this population.
Are serum endothelin-1 levels associated with obesity in adult Indonesian females?
Cross-Sectional (n=124)
No
Are serum endothelin-1 levels associated with obesity in adult Indonesian females?
Absolute Event Rate: 1.98% vs 1.53%
p-value: p=0.030
This study highlights a high prevalence of central obesity among Indonesian females, though endothelin-1 levels were comparable between sexes.
Endothelin-1 levels associate with obesity in Indonesian females; hypothesis-generating for endothelial pathways and should not yet change practice.
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Hartopo et al. (2023) conducted a cross-sectional in Obesity (n=124). Obesity (Class II) vs. Normoweight was evaluated on Serum endothelin-1 level (p=0.030). Among adult Indonesian females, class II obesity was associated with significantly higher serum endothelin-1 levels compared to normoweight individuals (1.98 vs 1.53 pg/mL, p=0.030).
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