The effect of N-methacryloyl aminosalicylic acid (NMSA) on the tensile bond strength between resin materials and bovine dentin and also its desensitizing efficacy on hypersensitive dentin were investigated.In case of a composite resin, significantly greater bond was obtained by a combined treatment with 10% citric acid containing 3% CuCl2 (10-3 solution) and NMSA-liner, than that of the control group treated by H3PO4 only. Bond strength of MMA/TBB system resin was also promoted by NMSA application. In the clinical evaluation, the application of NMSA-liner has relieved most cases of the dentin hypersensitivity immediately after even a simple coating. For obtaining the long term effect, the dentin surface should be treated at first by 10-3 solution, though the efficacy was eliminated after a few days in some cases. Accordingly, this material seems to be promising both in the field of conservative dentistry and adhesive dentistry.
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Tagami et al. (1987) studied this question.
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