The Changing Nature of Endometrial Cancer

The past decade has been a time of reappraisal of endometrial cancer. New concepts in its pathologic nature have been noted, its incidence has risen considerably, the theory of a hormonal relation has become widely accepted, and individualization of treatment has become commonplace. These changes have brought this complex lesion to the attention of increasing numbers of physicians.Pathological ReappraisalAlthough it is still correct to think of endometrial carcinoma as predominantly well-differentiated adenocarcinoma, there has been an increase in more virulent tumors in recent years. The most notable of these is the adenosquamous carcinoma, a mixed tumor with malignant . . .