PKCδ-null mice developed significantly more severe vein graft arteriosclerosis compared to wild-type mice (P < 0.01), associated with decreased smooth muscle cell apoptosis.
p-value: p=<0.01
1a) using the standard techniques of the
Leitges et al. (Thu,) conducted a other in Vein graft arteriosclerosis (n=24). PKCδ knockout vs. Wild-type (PKCδ+/+) was evaluated on Neointimal lesion area at 8 weeks (p=<0.01). PKCδ-null mice developed significantly more severe vein graft arteriosclerosis compared to wild-type mice (P < 0.01), associated with decreased smooth muscle cell apoptosis.
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