January 1, 2005Catheterization and Cardiovascular Interventions
Influence of stent surface topography on the outcomes of patients undergoing coronary stenting: A randomized double-blind controlled trial
Why the study?
Does a rough-surface stent improve late lumen loss in patients with significant stenosis in native coronary vessels compared to a smooth-surface stent?
Population
n=200 patients with significant stenosis in native coronary vessels
Comparison
rough-surface stent vs smooth-surface stent
Design
RCT, randomly assigned, double-blind
Authors
Discussion
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Member takes
Implication
Rough-surface stents meet equivalence criteria for late lumen loss; extends options for surface-modified drug-eluting designs.
Structured PICO
Does a rough-surface stent improve late lumen loss in patients with significant stenosis in native coronary vessels compared to a smooth-surface stent?
P
Population
n=200 patients with significant stenosis in native coronary vessels
I
Intervention
rough-surface stent
C
Comparator
smooth-surface stent
O
Outcome
late lumen losssurrogate
A rough stent surface is non-inferior to a conventional smooth stent surface regarding late lumen loss after implantation, suggesting it could be safely used to increase drug-storing capacity.
Cite This Study
Dibra et al. (2005) studied this question.