Penicillin fermentation is a batch process used for the industrial production of penicillin. In this paper, a fault detection scheme is designed for this process for a reliable operation. Since practical systems are subjected to disturbances and noises, designed scheme might be unreliable. To cope with this problem, optimization is also considered in the design by identifying an optimized parity vector directly from the process data without going into the details of system model using subspace aided approach.
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Khan et al. (2015) studied this question.
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