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Solitary pulmonary nodules are common on chest imaging, from lung cancer screening computed tomography scans to incidental findings on examinations performed for other reasons. Here, a 76-year-old man presented to the emergency department with fevers and cough, and computed tomography scan of the chest revealed a left upper-lobe consolidation and a 15-mm right lower-lobe nodule. The consolidation resolved with antibiotics; however, the nodule slowly grew over 2 years. Subsequent biopsy findings revealed neoplastic-appearing lymphoid cells with immunohistochemistry stains consistent with primary pulmonary mucosa-associated lymphoid tissue lymphoma. Given the slow growth of this neoplasm, the patient was managed with active surveillance.
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Schofield et al. (2024) studied this question.
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