A New and Flexible Synthesis of 4‐Hydroxypyridines: Rapid Access to Caerulomycins A, E and Functionalized Terpyridines

Simple, but yet unknown: 1,3-Diketones, ammonia, and carboxylic acids are the precursors for the efficient synthesis of 4-hydroxypyridines and the corresponding nonaflate derivatives. This provides simple and practical access to a variety of highly substituted pyridine derivatives, including antibiotic natural products such as caerulomycins A, E and functionalized terpyridines (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.