Answers are grounded in this paper and cite their sources.
All articles of this category A variety of quinolinecarboxaldehydes have been reacted with arenes in the Brönsted superacid, CF 3 SO 3 H (triflic acid) to give condensation products in good to excellent yields (52-99%). The quinolinecarboxaldehydes are significantly more reactive than 2-naphthalenecarboxaldehyde. It is proposed that the increased reactivity is due to the formation of dicationic, electrophilic intermediates. heterocycles - aldehydes - electrophilic aromatic substitutions - quinolines
No takes yet. Share an insight, caveat, or question.
Klumpp et al. (2000) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: