Selective catalytic reductions of nitriles are presented using the commercially available Ru‐Macho‐BH complex. A variety of aliphatic, aromatic and (hetero)cyclic nitriles including industrially important adipodinitrile are hydrogenated to the corresponding primary amines. Modelling suggests the reaction follows an outer sphere hydrogenation mechanism.
No takes yet. Share an insight, caveat, or question.
Neumann et al. (2015) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: