Key result
Male sex was associated with a significantly increased risk of sudden cardiac death compared to female sex (SRR 1.75) among residents in Xinjiang, China.
Why the study?
The epidemiological characteristics of sudden cardiac death in the multiethnic Xinjiang Uygur autonomous region have been largely unknown.
Observational (n=3,224,103)
Yes
Answers are grounded in this paper and cite their sources.
The incidence of sudden cardiac death in Xinjiang, China is 38.6 per 100,000 residents, with higher risks observed in men, specific ethnic groups (Uyghur and Kazakh), and areas with poor economic development.
BACKGROUND: The epidemiological characteristics of sudden cardiac death (SCD) in the autonomous region of Xinjiang Uygur have been largely unknown. This study aimed to evaluate the incidence and demographic risk factors of SCD in Xinjiang, China. METHODS: This retrospective study reviewed medical records from 11 regions in Xinjiang with different geography (north and south of the Tian Shan mountain range), gross domestic product, and ethnicity (Han, Uyghur, Kazakh, and Hui). SCD was defined as unexpected death due to cardiac reasons within 1 hour after the onset of acute symptoms, including sudden death, unexpected death, and nonviolent death. Monitoring was conducted throughout 2015. Demographic and mortality data were recorded and age-adjusted standardized risk ratio (SRR) was analyzed. RESULTS: Among 3,224,103 residents, there were 13,308 all-cause deaths and 1244 events of SCD (784 men and 460 women; overall incidence 38.6 per 100,000 residents). SCD was associated with age (χ2 = 2105.3), but not geography. Men had an increased risk of SCD compared with women (SRR: 1.75, 95% CI: 1.10-2.79). The risk of SCD was highest in residents of the Uyghur (SRR: 1.59, 95% CI: 1.05-2.42) and Kazakh (SRR: 1.92, 95% CI: 1.29-2.87) compared with those of the Han. Poor economic development was associated with elevated risk of SCD (SRR: 1.55, 95% CI: 1.02-2.38). CONCLUSION: SCD is an important public health issue in China. Our understanding of the demographic differences on SCD in Xinjiang, China may improve the risk stratification and management to reduce the incidence and lethality of SCD.
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Zhang et al. (2019) conducted an observational in Sudden cardiac death (n=3,224,103). Male sex vs. Female sex was evaluated on Age-adjusted incidence of sudden cardiac death (per 100,000 residents) (SRR 1.75, 95% CI 1.10-2.79). Male sex was associated with a significantly increased risk of sudden cardiac death compared to female sex (SRR 1.75) among residents in Xinjiang, China.
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