Derivatizing biomolecules with transition-metal fragments can be a useful approach to some biochemical problems, for example in labeling hormone receptors. The estradiol derivatives 1–4 deactivate the estradiol receptor to varying degrees, allowing conclusions to be drawn concerning the chemical environment of the binding site.
No takes yet. Share an insight, caveat, or question.
Vessières et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: