Key result
Inappropriate withholding of oral anticoagulation occurred in 51% of eligible patients with known atrial fibrillation, and improved guideline adherence could have prevented 22% of ischemic strokes.
Why the study?
Does strict adherence to antithrombotic guidelines prevent ischaemic strokes in patients with atrial fibrillation?
Population
Patients admitted with ischaemic strokes in whom the diagnosis of atrial fibrillation was known or…
Comparison
Strict adherence to antithrombotic guidelines… vs Current clinical practice
Design
Cross-sectional
Authors
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May identify modifiable gap in AF care; leaves open whether adherence interventions reduce strokes.
Cross-Sectional (n=89)
No
Does strict adherence to antithrombotic guidelines prevent ischaemic strokes in patients with atrial fibrillation?
A significant proportion of ischaemic strokes in AF patients could be prevented by strict adherence to oral anticoagulation guidelines.
Pisters et al. (2010) conducted a cross-sectional in Atrial fibrillation associated ischaemic stroke (n=89). Antithrombotic guideline adherence vs. Inappropriate anticoagulation was evaluated on Frequency of inappropriate anticoagulation on admission and theoretical number of preventable strokes. Inappropriate withholding of oral anticoagulation occurred in 51% of eligible patients with known atrial fibrillation, and improved guideline adherence could have prevented 22% of ischemic strokes.
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