Key result
Biatrial Cox-Maze IV cryoablation during concomitant cardiac surgery achieved a 4-year overall survival rate of 73.5% and freedom from atrial fibrillation of 38.6%.
Why the study?
The study was conducted to analyze the results of biatrial Cox-Maze IV cryoablation during combined heart surgeries.
Does biatrial Cox-Maze IV cryoablation during combined cardiac surgery provide long-term survival and freedom from atrial fibrillation in patients with persistent or long-term persistent AF?
Cohort (n=88)
Does biatrial Cox-Maze IV cryoablation during combined cardiac surgery provide long-term survival and freedom from atrial fibrillation in patients with persistent or long-term persistent AF?
Biatrial Cox-Maze IV cryoablation during concomitant cardiac surgery is safe and highly effective for restoring sinus rhythm initially, though freedom from atrial fibrillation declines to 38.6% at 4 years.
Answers are grounded in this paper and cite their sources.
Informs expectations after concomitant cryoablation; leaves open need for randomized comparisons before practice change.
Objective: To analyze the results of biatrial (BA) Cox-Maze IV cryoablation during combined heart surgeries. Methods: The study involved 88 patients who underwent BA cryoablation and concomitant cardiac surgery. The inclusion criteria were patients who underwent BA cryoablation and concomitant cardiac surgery between 2019 and 2021. The types of atrial fibrillation (AF) observed were as follows: persistent – 39 (44.3%) and long-term persistent – 49 (55.7%) cases. Results: The following procedures were performed: coronary artery bypass grafting (CABG) in 5 cases (5.7%), isolated valve repair in 67 cases (76.1%), and valve repair combined with CABG in 16 cases (18.2%). The aortic cross-clamping (ACC) time was 143 minutes [range: 120.5-161.5], and the cardiopulmonary bypass time was 193.5 minutes [range: 168.5-210]. BA Cox-Maze IV cryoablation was performed in all cases. The hospital mortality rate was 1.1%. Sinus rhythm was restored at the time of discharge in 81 patients (92%). Two patients (2.3%) received a permanent pacemaker. The survival rates at 1, 2, 3, and 4 years were 88.9%, 88.9%, 82.2%, and 73.5%, respectively. The rates of remaining free from AF at 1, 2, 3, and 4 years were 87.5%, 80.7%, 68.3%, and 38.6%, respectively. Conclusion: Cryoablation using the maze procedure as a concomitant step during cardiac surgery is a safe procedure with a high likelihood of restoring sinus rhythm.
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Комаров et al. (2024) conducted a cohort in Atrial fibrillation requiring concomitant cardiac surgery (n=88). Biatrial Cox-Maze IV cryoablation was evaluated on Overall survival and freedom from atrial fibrillation. Biatrial Cox-Maze IV cryoablation during concomitant cardiac surgery achieved a 4-year overall survival rate of 73.5% and freedom from atrial fibrillation of 38.6%.
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