The alkaloids rotundifoline, rhynchophylline, isorhynchophylline and isorotundifoline have been isolated from the leaves of Mitragyna stipulosa (D.C.), O. Kuntze (Rubiaceae). Traces of mitra-phylline were found in a few samples. The approximate concentration in various parts of the tree are recorded.
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Beckett et al. (1963) studied this question.
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