Three in one go: Unactivated dienes containing a cycloalkenyl moiety reacted with a range of substituted aryl halides in the presence of Pd(OAc)2/PPh3 to afford fused polycyclic heterocycles (see scheme). Three carbon–carbon bonds are formed in this domino reaction, which involves highly regioselective CC coupling and CH functionalization steps. DMF=N,N-dimethylformamide; Bn=benzyl, Ts=p-toluenesulfonyl.
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Hu et al. (2009) studied this question.