Key result
Vascular disease deaths in low- and middle-income countries surge by up to ~102% over three decades.
Why the study?
CVD prevalence and mortality have substantially increased in LMICs, prompting an evaluation of disease burden, surgical access, and disparities.
This review highlights an accelerating burden of vascular disease in LMICs and a profound, ongoing shortage of vascular surgery access compared to high-income countries.
Rising vascular deaths in LMICs may require expanded surgical capacity; leaves open optimal implementation strategies.
BACKGROUND: Cardiovascular disease (CVD) represents 32% of all global deaths. Studies have shown an increase in CVD prevalence and mortality with the most substantial increase in low-income and middle-income countries (LMICs). Within LMICs, we sought to 1) measure the burden of CVD with respect to aortic aneurysm (AA), ischemic stroke (IS), and peripheral arterial disease (PAD); 2) quantify surgical access to vascular surgery services; and 3) identify challenges and solutions to addressing disparities. METHODS: The Institute for Health Metrics and Evaluation Global Burden of Disease Results Tool was used to assess the global burden of CVD (AA, PAD, IS). Population data were extracted from the World Bank & Workforce data. A literature review was completed through PubMed. RESULTS: The number of deaths attributable to AA, PAD, and IS in LMICs increased by up to 102% between 1990 and 2019. Disability-adjusted life-years (DALYs) lost to AA, PAD, and IS in LMICs also increased by up to 67%. High-income countries (HIC) had a less considerable increase in deaths and DALYs during this time period. There are 101 and 72.7 vascular surgeons per 10 million people in the United States and United Kingdom, respectively. LMICs, such as Morocco, Iran, and South Africa have 10 times less this number. Ethiopia has 0.25 vascular surgeons per 10 million people, 400 times less than the United States. Interventions addressing these global disparities should address infrastructure and financing, data collection and sharing, patient knowledge and beliefs, and workforce development. CONCLUSIONS: Extreme regional discrepancies are evidence at a global scale. Identifying mechanisms to expand the vascular surgical workforce to meet the increasing need for vascular surgical access is imminent.
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Bencheikh et al. (2023) conducted a review in Aortic aneurysm, ischemic stroke, and peripheral arterial disease. Living in low-income and middle-income countries (LMICs) vs. Living in high-income countries (HIC) was evaluated on Number of deaths attributable to aortic aneurysm (AA), peripheral arterial disease (PAD), and ischemic stroke (IS) (up to 102% increase, p=<0.001). Between 1990 and 2019, deaths attributable to aortic aneurysm, peripheral arterial disease, and ischemic stroke in low- and middle-income countries increased by up to 102%.
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