Key result
Type 2 diabetes mellitus and hypothyroidism are associated with worse clinical outcomes and an increased incidence of major adverse cardiac and cerebrovascular events following percutaneous coronary intervention.
Why the study?
Both diabetes mellitus and hypothyroidism are associated with significant adverse impacts on patients undergoing PCI, and optimal management may improve clinical outcomes.
The presence of Type 2 diabetes mellitus and hypothyroidism significantly increases the risk of adverse cardiovascular events following percutaneous coronary intervention, highlighting the need for optimal management of these endocrine disorders.
The association between diabetes mellitus (DM) and hypothyroidism in cardiovascular disease (CVD) is well established.Both are associated with significant adverse impacts on patients undergoing percutaneous coronary interventions (PCI).DM is an independent predictor of adverse outcomes after drug-eluting stent (DES) implantation.Despite reasonable glycemic control in the peri-procedural period, DM is associated with worse clinical outcomes than non-diabetic patients.Hypothyroidism leads to higher cardiovascular comorbidities and is associated with an increased incidence of major adverse cardiac and cerebrovascular events (MACCE) than euthyroidism in PCI patients.Low T3 syndrome has also been associated with adverse outcomes in PCI patients.Diagnosis and optimal management of hypothyroidism may improve outcomes in CAD patients undergoing PCI.This review focus on the impact of T2DM and hypothyroidism in patients undergoing PCI.
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A 2022 study conducted a review in Coronary artery disease undergoing percutaneous coronary intervention. Type 2 diabetes mellitus and hypothyroidism vs. Non-diabetic and euthyroid patients was evaluated. Type 2 diabetes mellitus and hypothyroidism are associated with worse clinical outcomes and an increased incidence of major adverse cardiac and cerebrovascular events following percutaneous coronary intervention.
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