Key result
Patients with reduced left ventricular ejection fraction (<40%) 3 months after atrial fibrillation ablation had a nearly 5-fold higher risk of death or heart failure hospitalization compared to those with preserved ejection fraction (HR 4.97).
Why the study?
Does post-procedural LVEF category predict the composite outcome of death or heart failure hospitalization in patients with systolic dysfunction undergoing atrial fibrillation ablation?
Observational (n=150)
No
Does post-procedural LVEF category predict the composite outcome of death or heart failure hospitalization in patients with systolic dysfunction undergoing atrial fibrillation ablation?
Following AF ablation in patients with systolic dysfunction, achieving a post-procedural mid-range LVEF confers a comparable prognosis to preserved LVEF, whereas remaining with reduced LVEF is associated with significantly higher risk of death or heart failure hospitalization.
Warrants post-ablation LVEF monitoring for risk stratification; leaves open whether targeted interventions improve outcomes.
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Yazaki et al. (2020) conducted an observational in Atrial fibrillation with systolic dysfunction (n=150). Post-procedural reduced left ventricular ejection fraction (post-rEF, <40%) vs. Post-procedural preserved left ventricular ejection fraction (post-pEF, ≥50%) was evaluated on Composite of all-cause death and heart failure hospitalization (HR 4.97, 95% CI 1.63-17.06, p=<0.0001). Patients with reduced left ventricular ejection fraction (<40%) 3 months after atrial fibrillation ablation had a nearly 5-fold higher risk of death or heart failure hospitalization compared to those with preserved ejection fraction (HR 4.97).
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