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In the cat, the cortical arousal induced by reticular or nociceptive stimulation is more intense and more long-lasting after elimination of the caudal and medial part of the medulla than in preparations with intact brain. This difference is explained by the intervention of a phasic-ascending inhibitory bulbar control secondarily triggered by the mesencephalic activating system.
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Bonvallet et al. (1961) studied this question.
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