Poor CAD support hinders wide acceptance of asynchronous methodologies, and asynchronous design tools are far behind synchronous commercial tools. A new design flow, NCL/spl I.bar/X, based entirely on commercial CAD tools, targets a subclass of asynchronous circuits called null convention logic. NCL/spl I.bar/X shows significant area improvement over other flows for this subclass.
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Kondratyev et al. (2002) studied this question.
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